What is this medicine?
ACETAMINOPHEN; CHLORPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE (a set a MEE noe fen; klor fen IR a meen; dex troe meth OR fan; fen il EF rin) is a combination of a pain reliever, an antihistamine, a cough suppressant, and a decongestant. It is used to treat the aches and pains, cough, fever, congestion, runny nose, and sneezing of a cold. This medicine will not treat an infection.
How should I use this medicine?
This medicine is taken by mouth. Mix this medicine in a 4 ounce glass of water. Follow the directions on the package label. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years old for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain, tightness
dizziness, nervousness, or sleeplessness
fast, irregular heartbeat
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry eyes, mouth
loss of appetite
What may interact with this medicine?
Do not take this medicine with any of the following medications:
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
stimulant medicines like dextroamphetamine and others
This medicine may also interact with the following medications:
medicines for anxiety or sleep
medicines for blood pressure like atenolol, clonidine, doxazosin, methyldopa, metoprolol
medicines for chest pain like isosorbide dinitrate, nitroglycerin
medicines for enlarged prostate like tamsulosin
medicines for sleep during surgery
other medicines for cold, cough or allergy
other medicines with acetaminophen
St. John's Wort
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
cough that does not go away
cough with a lot of phlegm
high blood pressure
if you frequently drink alcohol containing drinks
taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
trouble passing urine
an unusual or allergic reaction to acetaminophen, chlorpheniramine, dextromethorphan, phenylephrine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant