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Aspirin, Caffeine, Dihydrocodeine Bitartrate Oral capsule

What is this medicine?

ASPIRIN; CAFFEINE; DIHYDROCODEINE (AS pir in; KAF een; dye hye droe KOE deen) is a pain reliever. It is used to treat moderate to severe pain.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. Do not use this medicine in children 12 years old or younger.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in behavior, mood

  • confusion

  • fast or slow heartbeat

  • feeling faint or lightheaded

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • ringing in the ears

  • tremors

  • unusual bleeding, bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • dry mouth

  • nausea, vomiting

  • passing urine more often

  • stomach upset

  • trouble sleeping

  • unusual sweating

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • alcohol

  • cidofovir

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • medicines for gout like probenecid, sulfinpyrazone

  • medicines that treat or prevent blood clots like enoxaparin, warfarin

  • methotrexate

  • other aspirin products

  • procarbazine

This medicine may also interact with the following medications:

  • barbiturate medicines for seizures, sleep

  • ginkgo biloba

  • medicines for anxiety, sleep

  • medicines for asthma, other breathing problems

  • medicines for high blood pressure or other heart problems

  • medicines for sleep during surgery

  • medicines for pain like buprenorphine, codeine, pentazocine

  • muscle relaxants

  • some medicines for allergies, colds

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature at 25 degrees C (77 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood clotting problems

  • drug abuse or addiction

  • head injury

  • heart, circulation problems

  • kidney disease

  • liver disease

  • lung or breathing disease

  • stomach ulcer, intestine problems

  • an unusual or allergic reaction to aspirin, caffeine, dihydrocodeine, codeine, or other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.

Do not suddenly stop taking it because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Too much aspirin can be very dangerous. Do not take aspirin or medicines that contain aspirin with this medicine. Many non-prescription medicines contain aspirin. Always read the labels carefully.

The medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.