What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. Do not take any additional medicines for Parkinson's disease without first consulting with your health care provider.
Entacapone may increase the side effects caused by Levodopa; Carbidopa such as nausea or restless movements. If you notice an increase in or the appearance of certain side effects that occurred only while you are taking Levodopa; Carbidopa, contact your physician. The dose of Levodopa-Carbidopa may need to be lowered. Do not decrease your medicine dose without asking your doctor or health care professional.
You may get dizzy or have difficulty controlling your movements. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness. Avoid alcoholic drinks.
If you find that you have sudden feelings of wanting to sleep during normal activities, like cooking, watching television, or while driving or riding in a car, you should contact your health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
You may experience a 'wearing off' effect prior to the time for your next dose of this medicine. You may also experience an 'on-off' effect where the medicine apparently stops working for anything from a minute to several hours, then suddenly starts working again. Tell your doctor or health care professional if any of these symptoms happen to you. Your dosage may need adjustment.
A high protein diet can slow or prevent absorption of levodopa. Avoid high protein foods near the time of taking this medicine to help prevent this problem. You may want to eat higher protein foods later in the day or in small amounts. Discuss your diet with your doctor or nutritionist.
Do not take iron supplements within 2 hours of taking this medicine. The iron may decrease the amount of levodopa in your system and decrease the effectiveness of the drug
If you have diabetes, you may get a false-positive result for sugar in your urine. Check with your doctor or health care professional.
This medicine may discolor your urine, saliva or sweat, making it look darker or red in color. This is of no cause for concern. However, this may stain clothing or fabrics.
There have been reports of increased sexual urges or other strong urges such as gambling while taking some medicines for Parkinson's disease. If you experience any of these urges while taking this medicine, you should report it to your health care provider as soon as possible.
You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.