What is this medicine?
INDOMETHACIN (in doe METH a sin) injection is a nonsteroidal antiinflammatory drug (NSAID). It is used to close a heart defect called patent ductus arteriosus (PDA) in a baby who was born early.
How should I use this medicine?
This medicine is for infusion into a vein. It is given by a health care provider in a hospital. It is usually given as three doses given at 12 to 24 hour intervals.
This drug is specifically for use in newborns.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
change in amount or color of urine
redness, blistering, peeling or loosening of the skin, including inside the mouth
unusual bleeding, bruising
yellowing of eyes, skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this medicine?
aspirin and aspirin-like medicines
medicines that treat or prevent blood clots like warfarin
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
steroid medicines like prednisone or cortisone
What if I miss a dose?
This does not apply.
Where should I keep my medicine?
This drug is only given in a hospital and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
an unusual reaction to indomethacin, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Your baby's condition will be watched closely while this treatment is given. Your baby will also receive regular blood tests and exams. Talk with your doctor or health care professional if you have any concerns.