What is this medicine?
IBUPROFEN; OXYCODONE (eye BYOO proe fen; ox i KOE done) is a pain reliever. It is used to treat moderate to severe pain for 7 days or less.
How should I use this medicine?
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black, tarry stools
changes in vision
difficulty passing urine
feeling faint or lightheaded
stomach pain or cramps
sudden weight gain or swelling
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
stomach upset, gas
What may interact with this medicine?
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
antihistamines for allergy, cough and cold
aspirin and aspirin-like drugs
barbiturates, like phenobarbital
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for stomach problems like dicyclomine, hyoscamine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for depression, anxiety, or psychotic disturbances
medicines for sleep
medicines for travel sickness like scopolamine
medicines that treat or prevent blood clots like warfarin
other narcotic medicines
other NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
some medicines for high blood pressure like enalapril
some medicines for Parkinson's disease like benztropine, trihexyphenidyl
steroid medicines like prednisone or cortisone
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
constipation or other intestinal problems
drink more than 3 alcohol containing drinks per day
drug abuse or addiction
lung or breathing disease, like asthma
recent head injury
an unusual or allergic reaction to oxycodone, codeine, ibuprofen, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
What should I watch for while using this medicine?
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Do not take naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
The medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Do not smoke cigarettes or drink alcohol; these may increase the irritation to your stomach when taking this medicine. If you get black, tarry stools or vomit up what looks like coffee grounds, call your doctor or health care professional at once.