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Polymyxin B Sulfate Solution for injection

What is this medicine?

POLYMYXIN B (pol i MIX in B) is a polymyxin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

How should I use this medicine?

This medicine is injected into a muscle, spinal fluid, or infused through a vein by a health care professional. It can also be given in the eye. Sometimes, this medicine is mixed with an irrigation solution which is then used to treat the skin. Follow the directions of your health care professional and the prescription label. Do not use your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • blurred vision

  • difficulty breathing or shortness of breath

  • confusion

  • dizziness

  • headache

  • loss of balance

  • muscle weakness

  • pain or difficulty passing urine

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • pain, irritation, or redness at the injection site

What may interact with this medicine?

  • anesthetics

  • amikacin

  • bacitracin

  • colistin

  • gentamicin

  • kanamycin

  • muscle relaxants

  • neomycin

  • paramomycin

  • some diuretics

  • streptomycin

  • tobramycin

  • vancomycin

  • verteporfin

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

You will be instructed on how to store this medicine, if needed. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease

  • lung disease

  • myasthenia gravis or other neuromuscular disease

  • an unusual or allergic reaction to polymyxin B, other antibiotics, other medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve or if you get new symptoms.