Health Library: ABCDEFGHIJKLMNOPQRSTUVWXYZ

Tolterodine Tartrate Oral capsule, extended-release

What is this medicine?

TOLTERODINE (tole TER a deen) is used to treat overactive bladder. This medicine reduces the amount of bathroom visits. It may also help to control wetting accidents.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Swallow whole, do not crush, cut, or chew. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • confusion

  • difficulty passing urine

  • fast, irregular heartbeat

  • hallucinations

  • memory problems

  • swelling in feet, hands

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in vision

  • constipation

  • dry eyes, mouth

  • headache

  • dizziness, drowsiness

  • stomach upset

What may interact with this medicine?

  • clarithromycin

  • cyclosporine

  • erythromycin

  • fluoxetine

  • medicines for fungal infections, like fluconazole, itraconazole, ketoconazole or voriconazole

  • medicines for memory problems like galantamine, donepezil, tacrine

  • vinblastine

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • difficulty passing urine

  • glaucoma

  • intestinal obstruction

  • irregular heartbeat or you have a family member with irregular heartbeat

  • kidney disease

  • liver disease

  • myasthenia gravis

  • an unusual or allergic reaction to tolterodine, fesoterodine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

It may take 2 or 3 months to notice the full benefit from this medicine. Your health care professional may also recommend techniques that may help improve control of your bladder and sphincter muscles. These techniques will help you need the bathroom less frequently.

You may need to limit your intake tea, coffee, caffeinated sodas, and alcohol. These drinks may make your symptoms worse. Keeping healthy bowel habits may lessen bladder symptoms. If you currently smoke, quitting smoking may help reduce irritation to the bladder muscle.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water, will help.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.