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Zidovudine Solution for injection

What is this medicine?

ZIDOVUDINE (zye DOE vue deen) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in emotions or moods

  • changes in hearing

  • dizziness

  • fever or chills, sore throat

  • muscle pain or weakness

  • nausea, vomiting, unusual stomach upset or pain

  • pain or difficulty swallowing

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • seizures

  • trouble passing urine or change in the amount of urine

  • unusual bleeding or bruising

  • unusually weak or tired

  • weight gain around waist, back, or thinning of face, arms, legs

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in skin or nail color

  • constipation

  • headache

  • loss of appetite

  • unusual taste in the mouth

What may interact with this medicine?

  • atovaquone

  • doxorubicin

  • fluconazole

  • ganciclovir

  • interferon

  • methadone

  • nelfinavir

  • other zidovudine medicines

  • phenytoin

  • probenecid

  • ribavirin

  • rifampin

  • ritonavir

  • stavudine, d4T

  • valproic acid

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • kidney disease

  • liver disease

  • low blood counts, like low white cell, platelet, or red cell counts

  • an unusual or allergic reaction to zidovudine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

This medicine can cause blood problems. You may have slow healing and a higher risk of infection while on this medicine. Try to avoid cutting or injuring yourself. Be careful not to damage to your teeth and gums when you brush or floss your teeth.