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You are 35 years or older; or will be 35 years or older at delivery.
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You have a history of pregnancy losses (miscarriages or stillbirths).
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You have an ongoing medical condition such as diabetes, thrombosis, psychiatric condition or a seizure disorder.
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You have been exposed to certain medications, alcohol, street drugs, chemicals, x-rays or infections during your pregnancy.
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You or your partner are from an ethnic origin in which a specific genetic condition is more common (e.g. sickle cell anemia in individuals of African-American descent and Tay Sachs disease in individuals of Ashkenazic Jewish descent).
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The results of a maternal serum screening test indicate that your baby is at increased risk for Down syndrome, trisomy 18 or spina bifida.
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You and your partner are blood relatives.
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An ultrasound evaluation has indicated an abnormality in the developing baby.
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You or your partner have a family history of a genetic condition (e.g. cystic fibrosis or muscular dystrophy), birth defect (e.g. cleft lip/palate or heart defect), or mental retardation.
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First trimester screening.
